East Avenue Medical Center-Department of Radiology
Dx2, Endokrin Flashcards Quizlet
NSIP is a rare condition with take part of approximately 25% of the interstitial lung diseases, which is far less than UIP pattern (60% of ILD). Clinical features of fibrotic NSIP (Commoner type of NSIP) is almost similar to the idiopathic pulmonary fibrosis (IPF / UIP). The HRCT appearance of pulmonary sarcoidosis varies greatly and is known to mimic many other diffuse infiltrative lung diseases. Approximately 60 to 70% of patients with sarcoidosis have characteristic radiologic findings.
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Clinical features (typical) of the idiopathic form: Middle-aged, never-smoker women. Dyspnea. Cough. Ground glass on HRCT.
Dyspnea. Cough.
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10 Once it has been established that the underlying disorder is fibrotic in nature, the NSIP is the diagnosis as Interstitial Lung Disease (ILD) with clinical significance, whereas only a part of subjects with ILA have clinically significant ILD. Eventually, both ILA and NSIP must be understood in the context of chronic fibrosing ILD and progressive ILD, which remains to be further investigated. Welcome to the Radiology Assistant Educational site of the Radiological Society of the Netherlands by Robin Smithuis MD Lung cysts are defined as radiolucent areas with a wall thickness of less than 4mm.
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Gross/Radiology. No honeycombing. Fibrosis usually lower lung zone. Patchy ground glass.
In 5 to 10% of patients the chest radiograph is normal. Usual interstitial pneumonia (UIP) is a histopathologic and radiologic pattern of interstitial lung disease, which is the hallmark pattern for idiopathic pulmonary fibrosis (IPF). Nonspecific interstitial pneumonia (NSIP) has variable clinical, pathologic, and radiologic manifestations. Cellular and fibrotic NSIP are the two main histologic subtypes and differ from one another in the degree of inflammation and fibrosis. The predominant finding in patients with nonspecific interstitial pneumonia (NSIP) is basal-predominant ground-glass opacity and/or reticular pattern, often with traction bronchiectasis, whereas usual interstitial pneumonia (UIP) has a spatially inhomogeneous, bilateral, peripheral, basal-predominant pattern of reticular opacities and honeycombing (, 1).
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The main feature of NSIP is temporally homogenous inflammation and fibrosis, as opposed … Organizing pneumonia is caused by inflammation 10 and may be idiopathic in nature, termed cryptogenic organizing pneumonia, or may occur secondary to infection, collagen vascular disease, or drug toxicity.
SCLERODERMA NSIP NSIP CT scan through the chest shows relatively symmetrical and peripherally positioned ground glass infiltrates with a region of subpleural sparing (red arrowhead)
Connective tissue diseases (CTDs) may be associated with a variety of lung abnormalities.
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Interstitiell lungsjukdom - gikitoday.com
In the images on your left you can appreciate again the spectrum of findings seen in NSIP. scleroderma-related interstitial lung disease (SSc-ILD) usual interstitial pneumonia (UIP) pattern: histologically indistinguishable from rheumatoid lung and idiopathic pulmonary fibrosis (IPF) an NSIP type can also occur; scleroderma-related pulmonary arterial hypertension (SSc-PAH) NSIP may be idiopathic or associated with collagen vascular diseases or exposure to drugs or chemicals. NSIP has a relative good prognosis and the majority of patients respond to treatment with corticosteroids. This outcome is quite different from that seen in UIP, which has a poor prognosis.